01. Contraindications
Hypersensitivity; state, accompanied by respiratory depression or marked CNS depression (alcohol poisoning, sleeping drugs, narcotic analgesics and other psychoactive drugs), the risk of suicide, addiction to substance abuse, concomitant use of MAO inhibitors (and the period within 2 weeks after withdrawal) , severe hepatic and / or renal failure, pregnancy (I term), breastfeeding (in the case of prolonged use), children up to age 1 year (parenteral) and up to 14 years (for ingestion).
02. Restrictions apply to
Opioid addiction, impaired consciousness different genesis, increased intracranial pressure, head injury, epilepsy, abdominal pain of unknown origin (acute abdomen), renal failure and / or liver.
From the digestive tract: dry mouth, nausea, vomiting, flatulence, abdominal pain, constipation / diarrhea, difficulty in swallowing.
With the cardiovascular system and blood (hematopoiesis, hemostasis): tachycardia, postural hypotension, syncope, collapse.
With the genitourinary system: difficulty urinating, dysuria, urine retention, menstrual disorders
Allergic reactions: hives, itching, rash, bullous eruption.
Other: dyspnea, with prolonged use - drug dependence, with abrupt cancellation - a withdrawal syndrome.
03. Application of pregnancy and breastfeeding
Appointment of tramadol possible during pregnancy (II and III trimester) only under strict medical supervision, if the benefits to the mother outweigh the risks to the fetus.
Category effects on the fetus by FDA - C.
04. Side effects
The nervous system and sensory organs: increased sweating, dizziness, headache, weakness, fatigue, confusion, paradoxical CNS stimulation (nervousness, agitation, anxiety, tremors, muscle spasm, euphoria, emotional ability, hallucinations), sleepiness, sleep disturbance , confusion, impaired coordination, unsteady gait, spasms of central origin (at / in the introduction of high doses or with concomitant administration of antipsychotic drugs (neuroleptics), depression, amnesia, cognitive impairment, paresthesia, blurred vision, taste.
